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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7f9a75120cbe63d9f1a1419b52018388645c67758372a0503e707d2429170e3' 
  AND token = '2eMSdAeL4QRVPLbx2wWmn/f2oDfZnYhWOV3kkIxmBzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}