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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf286d36ae9bc670e0b363c93fff247c9d66092fb1e2df495b4d5af8d249ccbf' 
  AND token = 'Y1z1UWo9HkGh3l5sX8jDYt7DFnsXBzJ3Bne2l0H1oM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}