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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63c167bcdd3453881bf457b2b017a98cb861799bdde3230c5591392c4a878be8' 
  AND token = '7NQ+OK9B50XaYw6Q3X8j6u5q3e+ij2/jhe7mD3BY8aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}