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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a843772afc5dee2e2fca9451428a49ae4921927d802547ce68cf402c2c3bfefd' 
  AND token = 'dgpv67X8WGVZ7fxU6q8Vbjw5Ef+qWRMwjlXaHS0kYew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}