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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45a84e722cfd3c17cf697a01cdf3e559663f75074bbf9c731d5836027776f88' 
  AND token = 'yowBSM5iDX7wTkEy56vNl35Hq0fZaOugkK2NjA1cdRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}