SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b83e55fb6078680198e0562914b06be10b7c46d60698bc3fdf6df371e45433' 
  AND token = '8M/EubsthaPHIPoW8S1q/vmV4IrPrL2JecRaEKjwbqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}