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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac39b294aa9a181765bc157e498d2e3bcf75a38e53b9aee8e6e33e6dfd317c2b' 
  AND token = 'cHP3iiDZTlrzzlVHHEIFjNPaPANfRT80coHh9ZLih4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}