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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2417573069b7a016a346721825338b30e38f46ad2b5d50a68b5b0f901360082d' 
  AND token = 'EYIgQBCMiaY6uKUkqenAl4FnPoULPMqWCrc8dODs5zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}