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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288fe1dc08edcaff2895019ee3a508031c5c856e2d33be472759b9c3dd94f439' 
  AND token = 'io11Bs72SFT6Yjn4eXigK0B37nng0MCPM8nkroW5IDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}