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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50002183041188fe3aebd9b3e73619f6b97b8ad8996ddc670764e60aa8dbfd4' 
  AND token = 'QA7jrYzRYMQi4vTbakPjA2EeEKty8VBLFjMsXIpBgnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}