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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d64234301967df20c232d11aca040a884d03504d85651889dd4d49a2c6f55eb' 
  AND token = 'GMq8XyFvqbic9N8+3avANeQkD1DVWX9mA6qFvEODVI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}