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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1547268298971291837a066ed602b6f438ab7fd97fe0e477c2e11a51fc6f919e' 
  AND token = 'phaw5BQzOaRuEf0i+AzPAqV2+iI1BfMwqFXHJkxFHUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}