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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa80d92e417a204137990720e4461cc6c65bb18c9f68c3d4705ce9037ef2397a' 
  AND token = 'isJywg0+UMtCAHgC5KSKYyfQ5mHzvwzleAvaWWmza2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}