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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d1582f9fefbf443c07489bd8f296b6dd9425e725e778f331b431f5be474862' 
  AND token = 'XrS4eATzVS1UMKkFVHm8VfFKQPF86m70s8GpRnuWNn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}