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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4852dd94ae5e8670f75f3976d0012981da44d2f207b09a3d4258261b046edf86' 
  AND token = 'ehYh3wxEVxidSLf+hRuEk2j62hNsjryaxqsA8T8HgQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}