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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef78870ca630a497ed268b7c5bd4d4792edaf387bb979b03171987469ac70ca1' 
  AND token = 'KHaA50i2K0N7PmtwhCkfBTdT93e+/U5mBxNS69ojsJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}