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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d33ef267f0711c29c60ae8d3e26ea4aca0f37b09a601951d07c222a84c4404' 
  AND token = 'G12lYAOPUibA2s8lObPqbydA+qr99sp7MKQ6PvIIFpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}