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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf492cd9e7e9fde0546555cad496d2076c2b6949609454f3bb7aeb12c3c8c3e6' 
  AND token = 'ubhD6YcapnjwGY132/iDYRFjQB/HFUkqx202zSkGJOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}