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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f4de69efce02c35acf2781bd57e16f2a8c72d9b6c6c8f4c5a3fb7285f611458' 
  AND token = 'UzLpYMMjUuzjLJOFHvhIHRN1We8B5886S1R1wohLmsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}