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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e64528bd7fab25c49ddf41d800eefb17ba8dd8f21cd2465858b5abb19453cc' 
  AND token = 'S2UCdVS9UxS5wVFdw2QLFg93UNCsHu6N+8fushV8jM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}