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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e522caf09f77a3dded023b13fefbb19405186d3ae212ba544c231bb6d90325' 
  AND token = 'abq0Pf2KV4zLBee6LGIXKrU27nG6yAZpiDO/wvulSEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}