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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c2d48e16ab9b18720fbebe70ea2b09dbed5f418661ac21120500c04805ee2d' 
  AND token = 'n8NE/5Qk1hvnDV6Mv6noJXMncyWbWZQaH5B2gYOt1uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}