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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e505dc56a419f7aca8816574db6c5a1b7051c9e8caae3a4a315ecb9da2aa47b4' 
  AND token = 'Z2DFW45yIDCwS9301XqpvGUn3NUDXX019pEpO8ih7SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}