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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca127084499722ecb2e41a57602d181fe8f751ae1e4b6f6d9b8a80ec7abe034' 
  AND token = 'JANFKT3994wiDoDxCFTT/WKFXFdY3AVBJA3G/mbSYv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}