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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e768d5924a3dc321d3382a25e9b49cfe2be0efea0b41ce07781cfe26f955d1' 
  AND token = 'Cw4FqiAcrD5KD0KGwBw/T1a2VqKCg9vM+k33ayzWWM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}