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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5f80ad318855b69644855b9234283a9c067cb98414eb64e309819b0cf927a9' 
  AND token = 'HLN7gmSC4DACAOkMctuROSWvay7irFBWyipZVP0nz6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}