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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f620fcdf8627a85382c6f0d2a68438e4b7ea383933ac432d109036bb940a23' 
  AND token = 'r1lSBYPeUt1y4z1qjCCW2hb9QWoijwBJIyYO3j50bsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}