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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5537587703623f21bc1e10a1ec60c387cbc2fdd49b4ca36c72cd859ca33e8081' 
  AND token = 'IH+3cVmwuXrdjxdeQDa77vkmI1J+oUYK7wYtBLAWhec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}