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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ba5a11f93665bc63d6f5f39c55f4fd1ef1b98373ef04df0da229660ef3c3abd' 
  AND token = 'K/dRS7ZlhMxg6SSDvtV2XUoYOXM+7Fp0SCkWRm609m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}