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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5af0591adae01d97f5185407653fcab2270e1e0011e9a51b8070e18125f4331c' 
  AND token = 'w/si4CxC/qN6LndMdvmdSTl+4lcL4lB6mVWeiwKhJBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}