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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '086905a568d2e10c9c00fbeeb78b27f4e1f01063c4f92fd10e9dabc16afcc06c' 
  AND token = 'zRQEXZ3TqjyJpj1GkyiYEfGn5kdbdQiP9VmzRUsCN9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}