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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f7bca7ecc284bde67f1555403be25bf612b20fd2664c1f9e81026157f9d0121' 
  AND token = 'QO+jPb0hkmsjYAtuOKKRYQc3F8mP+kTAw1+cakUsghg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}