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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4adef5a8a7d2109415c0ab80f9d97b4ec15ac0321b61c8b699ea430a538b8767' 
  AND token = 'P4YanJ4iguXltM47cZO5irVtqWjgAx80uM7Xh9abTJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}