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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd8f59bc849cbbe3fb6b2624393cf48314b2339e5d6d37e250f99420958f1cf' 
  AND token = 'M+qTkxyofQeuOR7To/6PQAnmDnQAHH2QdRjTzhrcZTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}