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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b941a10f5a74af72bc3665fad8129488273f65306060b756b1226bff6a0a42ce' 
  AND token = 'cCBtenFoDFQ0cjrXU37OGaLmJy6hvD2BtUyU0ZVWg4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}