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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c61626d52e27d321c49b0a761120f1a77fa6b2072eb40960b7e5567a0921b7a9' 
  AND token = 'O5qaM16PCuc9Jes//WriwMAOUtBjTjmVvd+gB45AjPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}