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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd2105786bd107752ab86b81c3f16890aceb2aff40fcae3c4c1fcf4ca3dc9198' 
  AND token = 'BjOx9+ckJCUMPpopl01CX3mQk530f7BOz2XvK18zDQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}