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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6235ce3eb0a38d24faf301552d811634e6c9a8aa354db6fcbc6f29c8d1c05945' 
  AND token = 'ZkWuDu0OYUfHWw9SrMZkqBA+fMKA3mxu2KpZ62yDETo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}