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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38208ffbf1b9508278b9c09f79201e395bcbb7dcfe14b0e58ff42c3e225772be' 
  AND token = 'DHj5l3IAFGDjoeP1/WdA9JdBcQU0G4VdJOsQdd/miGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}