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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111c6f4e143f2c3aefdc86d78a60d79654c2575ad5547a2db44c7d90de36fe9d' 
  AND token = 'NxPja1ub12bOp+jOPvmnyV6C1lfMZgXrfDxQaw28Mrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}