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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f9a2d2f842b22ade1928f807b6fb3b1a01ae38d75833306f7227041a5d6a9a' 
  AND token = 'YMubPtZX4TkWetD0Sx2squ2oOwwtEQvswtHnxQ0SpKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}