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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8000be6c871f0622ad654bba111506381c4596bdfb88c8bd9e1174a595781753' 
  AND token = 'nOKkEG3ATpGcoD0BzLW73EsL4H1dJDF09zgaLPlJEvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}