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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '386b86e6b8d80d2d42878f145f240475ca3795a7ed1c33e9490ebbcc0995add9' 
  AND token = 'so2Ckfpfp6APd0NI6ciynABAOgCrdp3Ruqbk5lh/pMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}