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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fa6cdfd8133df1ccaf45671640e7c8b4712b4b0e25581bf3f9c4aaae297c52c' 
  AND token = 'WThBBVE3e96XTxLcgdwS6NQ2QUEsVAvAmFPn5TNxjY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}