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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb9af6bf606584b6d4d43d89739085c63500b87b67a1a06bb669a078c0c2b354' 
  AND token = 'GwMKGzt8YfcIm+yt/vYl76mxe24D9XLRII2249aDy48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}