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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '562f58a979b3780b965b9ed0dd4e4d87e9ea22e548a69e39647fcae627941267' 
  AND token = '49a/2nWAl+nA/0ZIanaD5Amx4GD7Z1ZsJiDCq4aIK2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}