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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dc39c079a010e49222d435f167014a6dff4c74c4f53a85abfbaf49b53fa219a' 
  AND token = 'c05hSV14/t4jEh3g6615/8rLZNvBchkaSkyId+v54gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}