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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7e941d700dfa2bb2b4bcfa201b59967bea8d2c0dd45eb2fe8190d5fd37cc70a' 
  AND token = 'd0My2sMZPGftNqR6MkBEmiaG+yyxToCtdFBieMKZkBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}