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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5c25668768033f8900a49783df25a060d0ea2a8f67ab55045746b6a7a7ee39' 
  AND token = 'tPZ+j2vfBJah5PwjdoD4TSa0elgRfZj+ob1jWI23iWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}