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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c620cb4817b192d917de882e8a767e0248bae1402e6eac93f883a5672bb4fe0' 
  AND token = 'qeSZjAlbcl+Pxoju+WE28bdUYtySfd5Z0w7TMEA6pB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}